This is a list of the U.S. Billboard magazine Hot 100 Airplay number-ones of 1989.
| Issue Date | Song | Artist |
| January 7 | "Two Hearts" | Phil Collins |
| January 14 | "Two Hearts" | Phil Collins |
| January 21 | "When I'm With You" | Sheriff |
| January 28 | "Straight Up" | Paula Abdul |
| February 4 | "Straight Up" | Paula Abdul |
| February 11 | "Straight Up" | Paula Abdul |
| February 18 | "Lost In Your Eyes" | Debbie Gibson |
| February 25 | "Lost In Your Eyes" | Debbie Gibson |
| March 4 | "Lost In Your Eyes" | Debbie Gibson |
| March 11 | "The Living Years" | Mike + The Mechanics |
| March 18 | "Eternal Flame" | The Bangles |
| March 25 | "The Look" | Roxette |
| April 1 | "The Look" | Roxette |
| April 8 | "Like A Prayer" | Madonna |
| April 15 | "Like A Prayer" | Madonna |
| April 22 | "Like A Prayer" | Madonna |
| April 29 | "I'll Be There For You" | Bon Jovi |
| May 6 | "Forever Your Girl" | Paula Abdul |
| May 13 | "Forever Your Girl" | Paula Abdul |
| May 20 | "Rock On" | Michael Damian |
| May 27 | "I'll Be Loving You (Forever)" | New Kids On The Block |
| June 3 | "I'll Be Loving You (Forever)" | New Kids On The Block |
| June 10 | "Satisfied" | Richard Marx |
| June 17 | "Satisfied" | Richard Marx |
| June 24 | "Good Thing" | Fine Young Cannibals |
| July 1 | "Good Thing" | Fine Young Cannibals |
| July 8 | "If You Don't Know Me By Now" | Simply Red |
| July 15 | "Toy Soldiers" | Martika |
| July 22 | "Right Here Waiting" | Richard Marx |
| July 29 | "Right Here Waiting" | Richard Marx |
| August 5 | "Right Here Waiting" | Richard Marx |
| August 12 | "Right Here Waiting" | Richard Marx |
| August 19 | "Right Here Waiting" | Richard Marx |
| August 26 | "Cold Hearted" | Paula Abdul |
| September 2 | "Don't Wanna Lose You" | Gloria Estefan |
| September 9 | "Girl I'm Gonna Miss You" | Milli Vanilli |
| September 16 | "Girl I'm Gonna Miss You" | Milli Vanilli |
| September 23 | "Girl I'm Gonna Miss You" | Milli Vanilli |
| September 30 | "Miss You Much" | Janet Jackson |
| October 7 | "Miss You Much" | Janet Jackson |
| October 14 | "Miss You Much" | Janet Jackson |
| October 21 | "Listen to Your Heart" | Roxette |
| October 28 | "When I See You Smile" | Bad English |
| November 4 | "When I See You Smile" | Bad English |
| November 11 | "Blame It On The Rain" | Milli Vanilli |
| November 18 | "Blame It On The Rain" | Milli Vanilli |
| November 25 | "We Didn't Start the Fire" | Billy Joel |
| December 2 | "Another Day in Paradise" | Phil Collins |
| December 9 | "Another Day in Paradise" | Phil Collins |
| December 16 | "Another Day in Paradise" | Phil Collins |
| December 23 | "Another Day in Paradise" | Phil Collins |
| December 30 | "Another Day in Paradise" | Phil Collins |
Whitburn, Joel. The Billboard Book of Top 40 Hits. (2004) ISBN 0-8230-7499-4
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